Carmine, a red dye made of crushed-up South American insects, often lends its color to rosy lip and cheek cosmetics. (You’ll sometimes find it used to color foods, too.) Though some people are allergic to foods containing the dye, it’s rare to have a skin reaction to it, reports a 2011 study in Dermatitis. Even the Environmental Working Group’s Skin Deep Cosmetics Database rates the ingredient as a “low hazard.” Still, it may be a problem if you’re trying to avoid animal products or simply don’t want bugs in your cosmetics (we don’t blame you). In that case, choose rosy-hued products without carmine or cochineal extract in the ingredients.